Eric Dane, the American actor known for his television and film work, died on February 19, 2026, at the age of 53 after a battle with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease. His family shared that Dane spent his final days surrounded by loved ones — his wife Rebecca Gayheart, their two daughters, Billie and Georgia, and close friends. They asked for privacy as they navigate this difficult time and expressed gratitude for the support he received from fans around the world.
Dane’s career spanned more than three decades, beginning with guest roles in the early 1990s before rising to international recognition. He gained prominence for his portrayal of Dr. Mark Sloan, nicknamed McSteamy, on the long-running medical drama Grey’s Anatomy. From his first appearance in 2006 through the character’s return in 2021, Dane’s performance became a defining part of the series’ success and earned him widespread public affection.

Beyond Grey’s Anatomy, Dane appeared in a diverse range of film and television projects. He played Cal Jacobs in HBO’s acclaimed series Euphoria, a role he continued up until his death. Dane also starred as Captain Tom Chandler on TNT’s The Last Ship and took on roles in films including X-Men: The Last Stand, Marley & Me and Valentine’s Day.
Dane’s personal life — including a well-publicized controversy in 2009 and a period of treatment for prescription drug dependence in 2011 — was not without challenges. Still, he continued to work steadily and earned respect for his craft throughout his career. He and Gayheart married in 2004 and raised their two daughters together; although they separated in 2018, she remained a central figure in his life and caregiving in his final year.
In April 2025, Dane went public with his diagnosis of ALS, a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord and impairs muscle control over time. Less than a year later, he succumbed to the illness. During that period, Dane used his platform to become a visible advocate for ALS awareness and research. He spoke openly about his experience as a patient, participated in advocacy events — including a news conference in Washington addressing health care hurdles for ALS patients — and was honored by the ALS Network as Advocate of the Year in 2025 for his efforts to shine a light on the disease.
Colleagues and fans have remembered Dane not only for his memorable performances but also for the courage and openness he brought to discussions about ALS. As tributes have poured in, many have highlighted his dedication to his family, his generosity on and off the screen, and his commitment to helping others facing similar health challenges.
Eric Dane’s passing marks the loss of a distinctive television and film presence whose work and advocacy left a meaningful impact on audiences and the broader conversation around a devastating disease.
